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Low force Dynamic Fatigue Testing Machine for Tissues and Biomaterials

Model: UTDS-3EX, 3000N, 100HZ

UnitedTest Low-force dynamic fatigue testing machines (typically ≤5kN, down to mN-level precision) are specialized electromechanical systems engineered to simulate the cyclic mechanical loads that biological tissues and biomaterials endure in vivo. These machines are critical for validating the durability, biomechanical stability, and functional performance of tissue-engineered constructs (e.g., artificial cartilage, vascular grafts) and biomaterials (e.g., biodegradable polymers, ceramic scaffolds) before clinical translation.

General Introduction

Low force Dynamic Fatigue Testing Machine is often used to determine how a material will perform over time and repeated use.

UnitedTest Low force Dynamic Fatigue Testing Machine is focus on the tissue engineering industry, applies the principles of biology and engineering to the development of functional substitutes for damaged tissue. Mechanobiology provides insights into tissue physiology, disease development and relevant therapeutic strategies by understanding how mechanical forces induce changes at the molecular, cellular and tissue levels. These two fields focus heavily on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, cell differentiation, physiology, and disease. Thus, mechanical testing is an integral part of advancements in these emerging fields.


Biomaterial cells:  Serving as the basis for tissue regeneration, stem cells (such as mesenchymal stem cells) or already differentiated functional cells are typically used, expanded in vitro, and then implanted into a biological scaffold. 

Biological scaffold materials:  Provide three-dimensional structural support, simulating the extracellular matrix environment, divided into natural materials (such as collagen, chitosan) and synthetic materials (such as polylactic acid). 

Biocompatibility, biodegradability, and mechanical compatibility to promote cell adhesion, proliferation, and differentiation. 


When execute the fatigue testing at very low loads, load cell selection is vital to ensure the appropriate measurement accuracy and control. High precision small load range load cell and the compact designed test fixture, make machine suitable for the tissue engineering like biomaterial cells, biological scaffold materials, (such as collagen, chitosan) and synthetic materials (such as polylactic acid), surgical implant etc., industry fatigue testing and lab research. For loads in the sub-Newton range (e.g. down to 1 gram) an ultra-low capacity load cell can be used. In this particular case, we used a 10 N (1000 gram) load cell in conjunction with the UTDS-3EX. 


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Tissue engineering Test Surgical implants Test Heart stent test

Key Features

  • Load frame and driven type
  • Actuator
  • Control system, Software
  • Structures
  • Advantages
  • Data Acquisition & Analysis for Biomaterials

1), Frame is double column frame structure, servo liner actuator installed at upside of frame. Clamper will be installed on the corsshead and top of actuator piston rod;

2), Frame crosshead adjustment use leading screw rising and falling, manual clamping, elastic loosen structure, ensure the crosshead is reliable during test. And ensure the crosshead is locked unmoving at non-test condition.

3), Column outer surface processed by durionise, enhance the anti-wear ability, improve anti-corrosion ability, and more beautiful appearance.

4), With feature of compact structure, high stiffness, high centering, easy clamp test sample; can match various test fixture to extend test function.


Electronic Dynamic Testing Machine/Cyclic Testing Equipment

Fatigue testing on an elastomer

1), Servo liner actuator is the key part in this testing machine, the test output load through this actuator; with United Test technology self design, the actuator internally intall on the top side of frame, consist of actuator, servo motor, servo driving sytem, and load cell.

2), Servo liner actuator frequency limitation position have relief area, avoid the damage of out control.

3), Liner sensor with USA Schaevitz company LVDT, move smoothly, piston rod made by extra-fine process, surface chrome-plated polishing to Rα0.4u.

4), Between load cell and clamper connection, push-pull rod and clamper position have specialized gap elimination device, then improve the dynamic response ability.

1), One control chanel, with load, displacement, deformation three close-loop control,  these three control type smoothly switch.

2), Max. close-loop data flash frequency is 6Khz;

3), Controller A/D, D/A resolution is 16 bit, signal generate frequency is 0.001Hz~ 50HZ;

4), Signal generate waveform include sine wave, triangular wave, quare wave, sawtooth wave etc.,;

5), Two levels servo valve driving unit used to drive the servo valve, remote hydraulic pump used to remote control the hydraulic pump station.

6), controller with limitation parameter setting function, and protect function.  Can free setting the load up/ low limitation protection, frequency protection etc.,


Electronic Dynamic Testing Machine/Cyclic Testing Equipment

Cyclic test EN 397 Compression Testing Industrial Safety Helmets 

A new generation of fatigue testing system centered around a large electromagnetic motor as the actuator;
The directly driven electromagnetic motor operates stably with high repeatability, ensuring precise control of force and displacement;
The built-in electromagnetic actuator features low friction and high repeatability, offering a high response speed;
Capable of performing tests such as tension, compression, bending, shearing, creep, and relaxation;
Meets the stringent requirements of modern materials mechanics testing for high precision, high frequency, high stability, and durability;
Characteristics include oil-free, no seals, maintenance-free, long lifespan, high integration, easy installation, and small footprint;
Multiple fixtures and accessories are available for selection.

1. Environmental Friendliness
No hydraulic oil leakage or pollution
Low noise operation (≤70dB) allows placement in office areas
Energy-efficient (only consumes power during testing)
2. Cost Benefits
Initial investment: Lower than hydraulic systems
Maintenance: No hydraulic fluids, filters, or seals to replace
Running costs: Minimal power consumption
Space savings: Small footprint reduces laboratory space requirements
3. Performance Advantages
Precision: Backlash-free motion with high repeatability
Control flexibility: Smooth transition between load, displacement, and strain control
Safety: Dual-stage drive mechanisms and overload protection
Clean operation: Ideal for testing sensitive materials like medical devices
4. Ease of Use
Ergonomic design: Intuitive touchscreen or PC interface
Quick setup: Easy specimen installation with specialized fixtures
Automation: Programmable test sequences and data logging

Real-time monitoring: Simultaneous capture of force, displacement, strain, and cycle count (up to 10^9 cycles for long-term fatigue testing).
Biomechanical metrics: Automated calculation of fatigue life (S-N curves), modulus degradation, creep-fatigue interaction, and failure mode (brittle vs. ductile).
Compliance with biological testing standards: Pre-programmed test protocols for ISO, ASTM, and FDA guidelines for biomaterials.
Data export: Compatibility with bioinformatics tools for post-test analysis of tissue/biomaterial degradation.

Main Technical Specification

Max. dynamic load3000N;  Accuracy ±1%
Max. static load2100N
Machine class0.5 class
Test load accuract0.5% FS
Test space0-240mm
Displacement stroke30mm
Displacement accuracy0.1um
Test speed5um/s~0.8m/m
Test Frequency0.001HZ ~ 100HZ
Control modeLoad, displacement, deformation
Main test waveformSinusoidal wave, triangular wave, square wave, sawtooth wave etc.,
Dimensions1000*700*1200mm
Weight550kg
Standard Power220V, 50HZ, 1 phase
Working systemMS Win10/Win11 English
Load cellUSA, Vishay Celtron


Main Accessories

High Stiffness Frame1 set
Servo liner actuator1 set
Servo motor/driver (Japan Panasonic)1 set
Loadcel: (USA Vishay Celtron)1 set
LVDT (Japan Tamagawa liner displacement sensor)1 set
Tensile test fixture (optional according requirement)
Compression platen (100mm)1 set
Fully digital servo controller1 set
Professional testing software1 set
Computer1 set
Printer1 set
Documents (Manual, packing list, certificate)


Main Structure


Electronic Dynamic Testing Machine/Cyclic Testing Equipment


UTDS series Electronic Dynamic Universal Testing Machine mainly consist of parts as below:

1, movable loading platform, can 360 degree free adjusting, easy for sample test.

2, Imported actuator, Japan Panasonic driving system.

3, Data collection system, English software, static/dynamic controller.

4, USA Vishay celtron load cell.

 

6.1 Servo actuator

Actuator mounted on the top pf working table.

● Max. load capacity: 10000N.

● Effective stroke: +/-50mm (total 100mm)

● Actuator include Japan Tamagawa high accuracy displacement sensor.

● Actuator amplitude limitation position designed with buffer zone, avoid the damage caused by out of control.

● Include device to eliminate the gap clearance, minimize the side force, reduce the impact during high frequency test. 


Electronic Dynamic Testing Machine/Cyclic Testing Equipment

6.2, Load cell

● Use the USA Vishay Celtron load cell, 10KN, overload capacity 150%, mounted at front end of actuator piston, with self-lock nut. 

● Calibrated before delivery. 


6.3, Data collection system and controller

Servo control system include fully digitally servo controller, computer, software etc., 

1)Controller main consist of: 

● Controller frame SUPERTEST T8.3, max. upgrade to 6 channel. 

● With two sensor signal unit (load, displacement) 

● Signal generator unit

● Computer

2)Controller frame SUPERTEST T8.3 specification: 

● Control unit: fully digital PIDF control. 

● Frequency range: 0.01 ~15HZ, resolution: 0.01Hz

● Control waveform: Sine wave, Triangle wave, square wave, oblique wave, half of wave etc., 

● Control mode: Load, displacement close-loop control. 

● System with load cell calibration, zeroing etc., function. 

3)Main function of controller: 

● Controller with various corresponding software suite, can meet kinds of different test requirement. 

● With calibration system to help customer to calibrate the machine easily. 

With multi-control mode, can realize smooth swift, with automatically zeroing, save and recover PID setting, automatically data collection, sample protection function etc.,


Software

Main interface: 


Electronic Dynamic Testing Machine/Cyclic Testing Equipment

Electronic Dynamic Testing Machine/Cyclic Testing Equipment

Electronic Dynamic Testing Machine/Cyclic Testing Equipment

Critical Applications in Tissue Engineering & Biomaterials

1. Orthopedic Tissue Engineering
Fatigue testing of 3D-printed bone scaffolds (assessing durability under cyclic compression over 10^6 cycles)
Dynamic fatigue of cartilage constructs (evaluating glycosaminoglycan (GAG) retention under joint-like cyclic loading)
Tendon/ligament graft fatigue (testing tensile fatigue resistance of collagen-based constructs)
2. Cardiovascular Biomaterials
Pulsatile fatigue testing of biodegradable stents (assessing radial strength retention over cardiac cycles)
Cyclic flexure testing of vascular grafts (mimicking arterial wall deformation during blood flow)
Fatigue resistance of heart valve leaflets (dynamic bending/tensile loading to simulate valve opening/closing)
3. Soft Tissue Engineering
Fatigue testing of skin substitutes (cyclic stretching to mimic movement-induced deformation)
Bladder/ureteral scaffold fatigue (cyclic distension to simulate urine filling/emptying)
Neural tissue scaffolds (low-force cyclic shear loading to mimic spinal cord motion)
4. Biomaterial Development
Fatigue characterization of biodegradable polymers (PLGA, PCL) for implantable devices (tracking mechanical degradation as the material resorbs)
Ceramic scaffold fatigue (assessing crack propagation in hydroxyapatite-based bone grafts)
Composite biomaterials (e.g., polymer-fiber scaffolds for tissue regeneration) fatigue life validation


Compliance with Industry Standards


StandardApplication
ASTM F1813Fatigue testing of metallic bone plates/screws
ISO 10993-14Mechanical testing of degradable biomaterials
ASTM D7137Flexural fatigue of polymer biomaterials
ISO 7206-4Fatigue testing of hip joint implants (low-force components)
FDA 21 CFR Part 860Biomechanical testing of medical devices (tissue-engineered products)


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Beijing United Test Co., Ltd.