Mechanical fatigue damage is a key issue for soft tissues and tissue-derived materials, especially in musculoskeletal and cardiovascular applications; soft tissue fatigue experiments are often difficult to conduct and time-consuming, which hinders development in this field to some extent. However, recently developed constitutive models for soft tissue fatigue damage have made it possible to perform simulation-based fatigue analysis of tissues under various conditions. Computer simulations facilitate highly controlled and quantitative analyses to study the different effects of loading conditions and design features on tissue durability.

UnitedTest fatigue testing system is trusted by leading medical device manufacturers, universities, and research laboratories to determine the mechanical performance and durability limits of medical devices, biomaterials, tissues, and tissue engineering products. Our systems designed for tissue engineering and mechanical biology applications combine mechanical testing solutions that mimic physiological conditions of samples. In addition, UnitedTest has become a major global supplier of micro-dynamic testing equipment, which can be placed under an electron microscope and is suitable for inclusion in perfusion bioreactors. These complex micro-testing systems assist tissue engineers and cell biologists in conducting high-resolution research in the field of mechanobiology.

Evaluation of Fatigue Performance of Biomaterials

It is necessary to test the fatigue strength and long-term stability of biomaterials such as implants and scaffolds. For example, assessing the fatigue resistance of metal or polymer materials in the human environment ensures that implanted devices do not experience structural failure under long-term load (such as bone repair materials bearing body weight).

Durability Verification of Medical Devices

For medical devices such as joint replacement components and dental implants, it is required to simulate dynamic loads experienced during human movement (such as alternating stress during joint activities) and verify that their fatigue life meets the clinical usage requirements.

Safety Testing of Rehabilitation Equipment

Dynamic loading tests are conducted on rehabilitation devices (such as exoskeletons and walking aids) to ensure that they do not experience structural failure due to material fatigue within the user's activity range.

Research on Biomechanical 

Properties of Biological TissuesDynamic experiments analyze the stress distribution and damage mechanisms of soft tissues such as muscles and ligaments under dynamic loads, assisting in the design of surgical procedures and optimization of rehabilitation programs.

Common Testing Methods 

Include:Fatigue Testing under Stress Control: Testing material fatigue behavior under constant stress amplitude, and plotting S-N curves;

Random Load Fatigue Testing: Simulating random load spectra in actual working conditions to assess durability in complex environments;

High-Frequency Vibration Testing: Suitable for testing medical devices that require high-frequency dynamic response (such as joint prosthetics).

Beijing United Test Co.,Ltd. export@unitedtest.com offer the testing equipment of Fatigue Testing in Extending the Lifespan of Engineering Tissues. 

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