Information on the most widely used ASTM standards within the materials testing industry
ASTM F2118 is a standard test method for force - controlled constant - amplitude fatigue testing of acrylic bone cement materials. It is mainly used to evaluate the fatigue performance of acrylic bone cement commonly used in orthopedic surgeries, providing a unified testing basis for the research and development, production, and quality inspection of such materials. The following is a detailed introduction:
Core Scope and Purpose
Test Procedures and Key Parameters
| Test Link | Specific Requirements |
|---|---|
| Environmental Setup | The specimen is immersed in phosphate - buffered saline (PBS). The test chamber should be filled sufficiently to submerge the entire specimen. During the test, distilled water should be added in a timely manner to make up for the loss caused by evaporation. The temperature of the solution is controlled at 37°C, which is consistent with the human body temperature, simulating the physiological environment in which the bone cement works. |
| Loading Mode | A fully reversed sinusoidal cyclic tension - compression load is applied. This means the specimen alternates between tensile and compressive stresses during the test, which is closer to the alternating stress that bone cement bears in the human body during daily activities such as walking and running. |
| Test Approaches | There are two main test ideas. One is to conduct tests at three different stress levels to obtain the stress - cycle (S - N) curve of the bone cement, so as to comprehensively characterize its fatigue performance in a wide stress range. The other is to determine the fatigue life of the bone cement, with the general benchmark set at 5 million cycles. |
| Test Termination Conditions | The test stops when either the specimen fails (such as fracture or obvious damage), or the preset number of cycles (usually 5 million cycles) is completed. |
ISO 16402 Similar to ASTM F2118, this test method describes a variety of tests for evaluating the static and fatigue strength of acrylic resin-based bone cement. Constant amplitude, uniaxial, and tension-compression tests are performed to generate an S-N curve using dumbbell-shaped samples.
A four point bending fixture is placed in a liquid bath filled with Ringer's solution and maintained at 37 ° C. After quasi-static bending testing, fatigue testing is performed to generate a stress level/cycle number (S/N) curve.

Test Specimen Preparation and application
Test Specimen Preparation
Application Value:
It is widely used in the orthopedic medical material industry. In the R&D stage, it can help developers optimize the formula of acrylic bone cement; in the production quality control stage, it can be used to inspect the consistency of the fatigue performance of each batch of bone cement. Meanwhile, the test results can also provide reference data for regulatory agencies to evaluate the safety of such medical materials.
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